[{"Bold_text": "noun", "List Items": ["a change or variation occurring in the course of something.", "interchange or alternation, as of states or things.", "vicissitudes,successive, alternating, or changing phases or conditions, as of life or fortune; ups and downs:They remained friends through the vicissitudes of 40 years.", "regular change or succession of one state or thing to another.", "change ; mutation ; mutability ."]}]