<p><strong>verb (used with object)</strong></p><ul><li>to reduce or exhaust the strength of, as by exertion; make weary; fatigue (often followed by out): The long walk tired him.</li><li>to exhaust the interest, patience, etc., of; make weary; bore: Your stories tire me.</li><li>Synonyms: irk, exasperate</li></ul><p><strong>verb (used without object)</strong></p><ul><li>to have the strength reduced or exhausted, as by labor or exertion; become fatigued; be sleepy.</li><li>to have one's appreciation, interest, patience, etc., exhausted; become or be weary; become bored (usually followed by of): He soon tired of playing billiards.</li></ul><p><strong>noun</strong></p><ul><li>British Dialect: fatigue.</li></ul>